Working together to grow libraries in developing countries Chapter opener credits: Chapter 43, modified from © Getty Images 21000058038 Chapter 44, modified from © Getty Images 21000044598 Chapter 84, modified from © Corbis. Publishing Director: Linda Belfus Acquisitions Editor: William Schmitt Managing Editor: Rebecca Gruliow Publishing Services Manager: Tina Rebane Project Manager: Mary Anne Folcher Design Manager: Steven Stave Marketing Manager: John Gore Cover illustration is a detail from Opus 1972 by Virgil Cantini, Ph.D., with permission of the artist and Mansfield State College, Mansfield, Pennsylvania. Includes bibliographical references and index. Textbook of medical physiology / Arthur C. Library of Congress Cataloging-in-Publication Data Guyton, Arthur C. To the fullest extent of the law, neither the Publisher nor the Author assumes any liability for any injury and/or damage to persons or property arising out or related to any use of the material contained in this book. It is the responsibility of the practitioner, relying on their own experience and knowledge of the patient, to make diagnoses, to determine dosages and the best treatment for each individual patient, and to take all appropriate safety precautions. Readers are advised to check the most current information provided (i) on procedures featured or (ii) by the manufacturer of each product to be administered, to verify the recommended dose or formula, the method and duration of administration, and contraindications. As new research and experience broaden our knowledge, changes in practice, treatment and drug therapy may become necessary or appropriate. NOTICE Knowledge and best practice in this field are constantly changing. Permissions may be sought directly from Elsevier’s Health Sciences Rights Department in Philadelphia, PA, USA: phone: (+1) 2, fax: (+1) 2, e-mail: You may also complete your request on-line via the Elsevier homepage (), by selecting “Customer Support” and then “Obtaining Permissions”. No part of this publication may be reproduced or transmitted in any form or by any means, electronic or mechanical, including photocopying, recording, or any information storage and retrieval system, without permission in writing from the publisher. Kennedy Blvd., Suite 1800 Philadelphia, Pennsylvania 19103-2899 Professor and Chairman Department of Physiology and Biophysics University of Mississippi Medical Center Jackson, MississippiĮlsevier Inc. Guyton, M.D.† Professor Emeritus Department of Physiology and Biophysics University of Mississippi Medical Center Jackson, Mississippi †
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